5-nitro-pyridine-2-carboxylic acid aMide

5-nitro-pyridine-2-carboxylic acid aMide - Names and Identifiers

Name	2-Pyridinecarboxamide, 5-nitro-
Synonyms	5-Nitropicolinamide 5-Nitro-2-carboxaMide 5-Nitropyridine-2-carboxamide 2-Pyridinecarboxamide, 5-nitro- 5-nitro-pyridine-2-carboxylic acid amide 5-nitro-pyridine-2-carboxylic acid aMide
CAS	59290-34-5

5-nitro-pyridine-2-carboxylic acid aMide - Physico-chemical Properties

Molecular Formula	C6H5N3O3
Molar Mass	167.12
Density	1.476
Melting Point	246-247℃
Storage Condition	Sealed in dry,2-8°C

5-nitro-pyridine-2-carboxylic acid aMide - Introduction

2-Pyridinecarboxamide, 5-nitro-is an organic compound with the chemical formula C6H5N3O3. The following is a description of some of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 2-Pyridinecarboxamide, 5-nitro-a white to pale yellow crystalline powdery solid.
-Melting point: The melting point of the compound is about 145-146°C.
-Solubility: 2-Pyridinecarboxamide, 5-nitro-has low solubility in water, but is more soluble in some organic solvents such as ethanol, ether and chloroform.

Use:
-Medicine: 2-Pyridinecarboxamide, 5-nitro-is widely used as a raw material for insecticides, fungicides and preservatives in the pharmaceutical field.
-Laboratory research: This compound is also commonly used in organic synthesis reactions and laboratory research.

Preparation Method:
The preparation method of 2-Pyridinecarboxamide, 5-nitro-can be obtained by reacting pyridine-2-carboxylic acid with nitric acid:
1. First, the pyridine -2-carboxylic acid suspended in ice-cold concentrated nitric acid.
2. In the case of full stirring, slowly add concentrated sulfuric acid until the reactant is completely dissolved.
3. The reaction mixture was cooled to room temperature and precipitated.
4. Filter and wash the precipitate with cold water, and finally crystallize the product with ethanol to obtain pure product.

Safety Information:
- 2-Pyridinecarboxamide, 5-nitro-has certain toxicity and may cause risks to people and the environment.
-When using or handling this compound, follow appropriate safe operating procedures, including wearing appropriate personal protective equipment such as gloves, glasses, and laboratory clothing.
-Avoid contact with skin, eyes and respiratory system, and avoid ingestion or inhalation.
-Be aware of fire, explosion and ionizing radiation hazards when storing and handling this compound.

Last Update：2024-04-09 15:17:58